Correction to Fragment-Based Identification of Influenza Endonuclease Inhibitors
نویسندگان
چکیده
Page 6445. In Table 1, the IC50, pIC50, and LE values of compound 5 are incorrect. They should be 68± 11 nM, 7.2, and 0.89, respectively. The reported values correspond to a different chemical entity; this error was caused by a mislabeling-error in screening of the fragment library. The main text is unaffected by this error. Compound 5 was only discussed as a tolerated structural analogue of compound 1, which remains true despite our error. The corrected Table 1 is shown here.
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Crystallographic fragment screening and structure-based optimization yields a new class of influenza endonuclease inhibitors.
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